Review of recent evidence with translation to practice for the advanced
practice nurse (APN) role is presented using a case study module for
“Complications Associated With Oral Anticoagulation Therapy.” The study
results showed that bleeding complications were most often due to
gastrointestinal bleeding associated with anticoagulants (dabigatran 80%
and warfarin 48%). The implications and clinical relevance of these
findings for APNs are discussed highlighting best evidence.
The purpose of this study was to compare bleeding complications associated with dabigatran and
warfarin in a sample of patients with a diagnosis of
anticoagulant-related bleeding complications admitted through the ED.
Using a prospective medical record review of eligible patients, the
authors abstracted data on the basis of agree-upon definitions of all
variables, for example, “major” and “life-threatening” hemorrhages were
differentiated on the basis of reduction in hemoglobin measurements and
the number of units of blood transfused over a period of time, and they
performed a blind review of a sample of their records to ensure
interrater reliability. The investigators provide only the briefest of
descriptions of their data analysis, stating, “Descriptive statistics
were used and 95% confidence intervals were calculated.” They do not
elaborate any further.
Read full article: Complications Associated with Oral Anticoagulation Therapy
Howard, Patricia Kunz PhD, RN, CEN, CPEN, NE-BC, FAEN, FAAN
Advanced Emergency Nursing Journal:
doi: 10.1097/TME.0b013e3182a9e9a2
Research to Practice
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